Electrospinning for the Modification of 3D Objects for the Potential Use in Tissue Engineering

Technologies

Uwe Güth¹  Manasi Palachandran²  Carlotta Wolfschmidt²  Lisa Brandstäter²  Fynn Ole Wadehn²  Mika Letmate²  Laura Bauer²  Timo Grothe²  Andrea Ehrmann² 

[1] Department of Physical and Biophysical Chemistry (PC III), Faculty of Chemistry, Bielefeld University, 33615 Bielefeld, Germany;Faculty of Engineering and Mathematics, Bielefeld University of Applied Sciences, 33619 Bielefeld, Germany;

关键词: needleless electrospinning;    poly(lactic acid) (PLA);    poly(acrylonitrile) (PAN);    nanospider;    cell adhesion;    cell proliferation;   

DOI  :  10.3390/technologies10030066

来源: DOAJ

【 摘 要 】

Electrospinning is often investigated for biotechnological applications, such as tissue engineering and cell growth in general. In many cases, three-dimensional scaffolds would be advantageous to prepare tissues in a desired shape. Some studies thus investigated 3D-printed scaffolds decorated with electrospun nanofibers. Here, we report on the influence of 3D-printed substrates on fiber orientation and diameter of a nanofiber mat, directly electrospun on conductive and isolating 3D-printed objects, and show the effect of shadowing, taking 3D-printed ears with electrospun nanofiber mats as an example for potential and direct application in tissue engineering in general.

【 授权许可】

Unknown