Super pregnancy in a BALB/c mouse superovulated with PMSG

Laboratory Animal Research

Mojtaba Kafi¹  Mohammad Hossein Nooranizadeh¹  Hanieh Vaseghi¹  Asghar Mogheiseh¹  Masood Sepehrimanesh² 

[1] Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University;Gastroenterohepatology Research Center, Shiraz University of Medical Sciences;

关键词: Super pregnancy;    superovulation;    mice;    PMSG;   

DOI  :  10.5625/lar.2017.33.3.280

来源: DOAJ

【 摘 要 】

Abstract This paper reports a case of super pregnancy in a BALB/c mouse pregnant with 30 pups following induction of superovulation using a PMSG-hCG protocol. Superovulation was induced in 10 mice by injecting 5 IU PMSG followed by 5 IU hCG 48 hours later. Immediately after injection of hCG, animals were placed with males at a ratio of 1 to 1 for 24 hours. On day 14 after mating, animals were killed by cervical dislocation and the uterus was examined for pregnancy and the number of fetuses. The mean (±SEM) number of fetuses observed in ten mice was 5.4±3.18 with an unexpectedly super pregnant mouse bearing 30 fetuses on day 14 of pregnancy.

【 授权许可】

Unknown