Antibiotic-Resistant Enterobacteriaceae in Wastewater of Abattoirs

Antibiotics

JürgenA. Bohnert¹  Timo Homeier-Bachmann²  PhillipK. Lübcke²  Dirk Zimmermann³  Katharina Schaufler⁴  StefanE. Heiden⁴  Lisa Bachmann⁵ 

[1] Friedrich Loeffler-Institute of Medical Microbiology, University Medicine Greifswald, 17475 Greifswald, Germany;Friedrich-Loeffler-Institut, Institute of Epidemiology, 17493 Greifswald-Insel Riems, Germany;Greenpeace e.V., 20547 Hamburg, Germany;Institute of Pharmacy, University of Greifswald, 17489 Greifswald, Germany;Leibniz-Institut für Nutztierbiologie, Institute of Nutritional Physiology “Oskar Kellner”, 18196 Dummerstorf, Germany;

关键词: MDR;    slaughterhouse;    wastewater;    resistance;    Enterobacteriaceae;   

DOI  :  10.3390/antibiotics10050568

来源: DOAJ

【 摘 要 】

Antibiotic-resistant Enterobacteriaceae are regularly detected in livestock. As pathogens, they cause difficult-to-treat infections and, as commensals, they may serve as a source of resistance genes for other bacteria. Slaughterhouses produce significant amounts of wastewater containing antimicrobial-resistant bacteria (AMRB), which are released into the environment. We analyzed the wastewater from seven slaughterhouses (pig and poultry) for extended-spectrum β-lactamase (ESBL)-carrying and colistin-resistant Enterobacteriaceae. AMRB were regularly detected in pig and poultry slaughterhouse wastewaters monitored here. All 25 ESBL-producing bacterial strains (19 E. coli and six K. pneumoniae) isolated from poultry slaughterhouses were multidrug-resistant. In pig slaughterhouses 64% (12 of 21 E. coli [57%] and all four detected K. pneumoniae [100%]) were multidrug-resistant. Regarding colistin, resistant Enterobacteriaceae were detected in 54% of poultry and 21% of pig water samples. Carbapenem resistance was not detected. Resistant bacteria were found directly during discharge of wastewaters from abattoirs into water bodies highlighting the role of slaughterhouses for environmental surface water contamination.

【 授权许可】

Unknown