Added value of patient-reported outcome measures (PROMs) after an acute stroke and early predictors of 90 days PROMs

Journal of Patient-Reported Outcomes

Eva Aurin¹  Maria Baladas²  Marta Rubiera²  Estefania Montiel²  Marc Ribo²  Ester Sanchez-Gavilan²  Carlos A. Molina²  Sofia Lallanas²  Maria Gutierrez³  Carolina Watson³  Yolima Cossio³ 

[1] Innovation and Digital Health, Hospital Universitari Vall d’Hebron;Stroke Unit - HARMONICS research group, Hospital Universitari Vall d’Hebron, Vall d’Hebron Barcelona Hospital Campus;Value Based Health Care, Hospital Universitari Vall d’Hebron;

关键词: Depression;    Anxiety;    Stroke;    PROMs;    Outcomes;    Value based health care;   

DOI  :  10.1186/s41687-022-00472-9

来源: DOAJ

【 摘 要 】

Abstract Introduction Value-based health care represents a patient-centered approach by valuing Patient-Reported Outcome Measures (PROMs). Our aim was to describe the additional value of PROMs after an acute stroke over conventional outcome measures and to identify early predictors of poor PROMs. Methods Acute stroke patients discharged from a tertiary care hospital followed by a web/phone-based PROMs collection program in the post hospitalization phase. Main PROMs involve anxiety and depression (HADS) (each defined by HADS ≥ 10) and global physical (PHY-) and mental (M-) health (PROMIS-10). PROMIS cut-off raw values of normality were: PHY-PROMIS ≥ 13 and M-PROMIS ≥ 11. An overall health status (OHS) from 0 to 100 was also determined. PROMs related to the different modified Rankin Scale (mRS) grades were defined. Early predictors of PROMs were evaluated. Results We included 1321 stroke patients, mean age 75 (± 8.6) and 55.7% male; 77.7% returned home. Despite a favorable mRS at 3 months (< 3), a relevant rate of patients considered without symptoms or with mild disability showed unfavorable results in the measured PROMs (8% unfavorable OHS, 15% HAD-depression, 12.1% HAD-anxiety, 28.7% unfavorable M-PROMIS and 33.1% unfavorable PHY-PROMIS results). Along follow-up, only PHY-PROMIS and OHS showed significant improvement (p < 0.01 and 0.03, respectively). The multivariate analysis including discharge variables showed that female sex, higher discharge mRS and discharge to socio-rehabilitation-center (SRC) were independent predictors of unfavorable results in PROMs (p < 0.01). When adding 7 days PROMs results, they emerged as the strongest predictors of 3 months PROMs. Conclusions A high proportion of stroke patients show unfavorable results in PROMs at 3 months, even those with favorable mRS, and most results obtained by PROMs during follow-up continued to indicate alterations. Female sex, mRS and discharge to SRC predicted unfavorable results in PROMs, but the strongest predictors of 3 months PROMs were the results of the 7 days PROMs.

【 授权许可】

Unknown