AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR AND CALCIUM ANTAGONIST COMBINATION IN PHARMACOTHERAPY OF ARTERIAL HYPERTENSION

Кардиоваскулярная терапия и профилактика

O. V. Budik¹  K. V. Ovsyannikov¹  S. V. Gatsura¹  L. L. Kirichenko¹  A. N. Golosova¹  A. V. Fedorov² 

[1] A.I. Evdokimov Moscow State Medico-Stomatological University;Central Clinical Hospital, Russian Federal Customs Service, Moscow;

关键词: arterial hypertension;    antihypertensive combination therapy;    calcium antagonists;    angiotensin-converting enzyme inhibitors;    microcirculation;    endothelial dysfunction;   

DOI  :  10.15829/1728-8800-2014-1-64-68

来源: DOAJ

【 摘 要 】

The paper focuses on the justification for preferential administration of antihypertensive combination therapy. Pharmacotherapeutic features of starting the treatment with a combination of angiotensin-converting enzyme inhibitors (ACEI) and calcium antagonists (AC) are reviewed. The authors also present the latest evidence on the ACEI/AC combination effects on such vascular parameters as microcirculation and endothelial dysfunction.

【 授权许可】

Unknown