Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip

Sensors

Yung-Shin Sun¹  Jin-Cherng Hsu¹  Chang-Jyun Li¹ 

[1] Department of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan;

关键词: optical fiber sensor;    surface plasmon resonance;    biosensor;    microfluidic chip;   

DOI  :  10.3390/s17010063

来源: DOAJ

【 摘 要 】

A curved D-type optical fiber sensor (OFS) combined with a microfluidic chip is proposed. This OFS, based on surface plasmon resonance (SPR) of the Kretchmann’s configuration, is applied as a biosensor to measure the concentrations of different bio-liquids such as ethanol, methanol, and glucose solutions. The SPR phenomenon is attained by using the optical fiber to guide the light source to reach the side-polished, gold-coated region. Integrating this OFS with a polymethylmethacrylate (PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are recorded. Experimentally, the sensitivity of the current biosensor was calculated to be in the order of 10−5 RIU. This microfluidic chip-integrated OFS could be valuable for monitoring subtle changes in biological samples such as blood sugar, allergen, and biomolecular interactions.

【 授权许可】

Unknown