Targeted Radionuclide Therapy: New Advances for Improvement of Patient Management and Response

Cancers

KatherineA. Vallis¹  Javian Malcolm¹  BoonQ. Lee¹  Nadia Falzone¹ 

[1] CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford OX37DQ, UK;

关键词: patient management;    precision medicine;    targeted radionuclide therapy;    prostate cancer;    neuroendocrine cancer;   

DOI  :  10.3390/cancers11020268

来源: DOAJ

【 摘 要 】

Compared to external beam radiotherapy, targeted radionuclide therapy (TRT) allows for systemic radiation treatment of metastatic lesions. Published work on recent strategies to improve patient management and response to TRT through individualising patient treatment, modifying treatment pharmacokinetics and increasing anticancer potency are discussed in this review, with a special focus on the application of clinically evaluated radiolabelled ligands and peptides in the treatment of neuroendocrine and prostate cancers.

【 授权许可】

Unknown