Intra-arterial tirofiban in a male nonagenarian with acute ischemic stroke: A case report

Open Life Sciences

Shi Xiaolei¹  Gu Ao²  Yang Qian²  Ding Xianhui²  Zhou Zhiming³ 

[1] Wuhu, China;Department of Neurology, The First Affiliated Hospital, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui Province, China;Department of Neurology, The First Affiliated Hospital, Yijishan Hospital of Wannan Medical College;

关键词: stroke;    nonagenarian;    endovascular;    intra-arterial;    tirofiban;   

DOI  :  10.1515/biol-2019-0057

来源: DOAJ

【 摘 要 】

Nonagenarians with acute ischemic stroke tend to have a higher mortality and morbidity than younger patients. Tirofiban is a glycoprotein IIb/IIIa antagonist that has a therapeutic potential for ischemic stroke. Here, we provide a case report of a 93-year-old male patient with acute ischemic stroke. He presented with right-sided hemiparesis for 2 hours (National Institute of Health Stroke Scale, NIHSS = 23). Immediate treatment with endovascular tirofiban infusion achieved an improvement of intracranial blood flow and a progressively decreased NIHSS one day after admission (NIHSS = 16) and then seven days after admission (NIHSS = 7). After a follow-up of 90 days, the modified ranking score was 2. This case report suggests that endovascular application with tirofiban may be a favorable option for treating nonagenarians presenting with acute ischemic stroke and warrants further study.

【 授权许可】

Unknown