期刊论文详细信息
Molecules | |
Catalytic Asymmetric Nitro-Mannich Reactions with a Yb/K Heterobimetallic Catalyst | |
关键词: nitro-Mannich; ytterbium; heterobimetallic; asymmetric catalysis; amide-based ligand; | |
DOI : 10.3390/molecules15031280 | |
来源: DOAJ |
【 摘 要 】
A catalytic asymmetric nitro-Mannich (aza-Henry) reaction with rare earth metal/alkali metal heterobimetallic catalysts is described. A Yb/K heterobimetallic catalyst assembled by an amide-based ligand promoted the asymmetric nitro-Mannich reaction to afford enantioenriched anti-b-nitroamines in up to 86% ee. Facile reduction of the nitro functionality allowed for efficient access to optically active 1,2-diamines.
【 授权许可】
Unknown