Functional characterization of biomedical potential of biosurfactant produced by Lactobacillus helveticus

Biotechnology Reports

Baljeet Singh Saharan¹  Deepansh Sharma¹ 

[1] Department of Microbiology, Kurukshetra University, Kurukshetra 136 119, India;

关键词: Biosurfactant;    Glycolipid;    Antimicrobial;    Antiadhesive;    Anti-Biofilm;   

DOI  :  10.1016/j.btre.2016.05.001

来源: DOAJ

【 摘 要 】

Various lactic acid bacteria (LAB) have been isolated and screened for biosurfactant production and their biomedical and food applications. Additionally, various different concentrations of the biosurfactant (0.625–25 mg ml−1) were used to evaluate its antimicrobial and antiadhesive potential against a range of pathogenic microorganisms. Biosurfactant was found to be stable to pH changes over a range of 4.0-12.0, being most effective at pH 7 and showed no apparent loss of surface tension and emulsification efficiency after heat treatment at 125 °C for 15 min. Present study demonstrated that biosurfactant obtained from Lactobacillus helveticus has the ability to counteract effectively the initial deposition of biofilm forming pathogens to silicone surfaces and to significantly sluggish biofilm growth.

【 授权许可】

Unknown