Clinical and Echocardiographic Findings in an Aged Population of Cavalier King Charles Spaniels

Animals

Jorge Prieto Ramos¹  Simon Swift²  Gabriel De La Fuente Oliver³  Laura Saderi⁴  Andrea Corda⁵  Brendan Corcoran⁶  AnneT. French⁷  KimM. Summers⁸ 

[1] Anicura Uribe Kosta Clinica Veterinaria, 48600 Sopelana, Spain;College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA;Departamento de Ciencia Animal, Universitat de Lleida-Agrotecnico-CERCA, 25198 Lleida, Spain;Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy;Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy;Royal (Dick) School of Veterinary Medicine, Easter Bush Campus, University of Edinburgh, Midlothian EH25 9RG, UK;School of Veterinary Medicine, Ross University, Two mile hill st., Michael BB11093, Barbados;Translational Research Institute, Mater Research Institute-University of Queensland, 37 Kent St, Wooloongabba, QLD 4102, Australia;

关键词: myxomatous mitral valve disease;    echocardiography;    mitral valve degeneration;    mitral valve prolapse;    cardiac remodelling;    dog;   

DOI  :  10.3390/ani11040949

来源: DOAJ

【 摘 要 】

Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. It varies from dogs without clinical signs to those developing left-sided congestive heart failure, leading to death. Cavalier King Charles Spaniels (CKCSs) are particularly susceptible to MMVD. We hypothesised that within the elderly CKCS population, there is a sub-cohort of MMVD-affected dogs that do not have cardiac remodelling. The objectives of the present study were (i) to determine the prevalence and the degree of cardiac remodelling associated with MMVD; and (ii) assess the effect of age, gender, and body weight on echocardiographic status in a population of aged CKCSs. A total of 126 CKCSs ≥ 8 years old were prospectively included. They all had a physical and echocardiographic examination. A systolic murmur was detected in 89% of dogs; the presence of clinical signs was reported in 19% of them; and echocardiographic evidence of MMVD was described in 100%. Despite the high prevalence, 44.4% of the dogs were clear of echocardiographic signs of cardiac remodelling. Age was significantly associated with the presence and severity of cardiac remodelling and mitral valve prolapse. Our results showed that a proportion of elderly CKCS with confirmed MMVD did not undergo advanced stages of this pathology.

【 授权许可】

Unknown