HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS

Ciência Animal Brasileira

Mariana B. Rodrigues Faleiro¹  Luiz Augusto Batista Brito¹  Aline Maria Vasconcelos Lima¹  Veridiana Maria B. Dignani de Moura¹  Fábio Luiz da Cunha Brito²  Adriana da Silva Santos³ 

[1] Escola de Veterinária e Zootecnia da Universidade Federal de Goiás, Goiânia, GO, Brasil;Instituto Qualittas de Pós-Graduação, Goiânia, GO, Brasil;nstituto Federal Goiano, Urutaí, GO, Brasil.;

关键词: canine visceral leishmaniasis;    conjunctiva;    dog;    eye;    lacrimal gland;   

DOI  :  10.1590/1089-6891v16i426859

来源: DOAJ

【 摘 要 】

Canine visceral leishmaniasis (CVL) is a disease with multisystemic injuries, and among the various tissues affected, the third eyelid (TE) is often involved. This ocular adnexa has been studied for the leishmaniasis pathogenesis elucidation and for diagnosis advance. This study aimed to carry out the parasite immunodetection and evaluate histologic lesions in TE of Leishmania (leishmania) chagasi naturally infected dogs. Twenty-six TE samples from infected dogs were submitted to histologic evaluation and to immunohistochemistry for Leishmania sp. The main lesion observed in the third eyelid conjunctiva (TEC) was lymphoplasmacytic inflammation, with Mott cells and parasitized histiocytes. Additionally, loss of epithelial stratification, ulceration, goblet cells thinning or hyperplasia were often found. The same inflammatory pattern was observed in the third eyelid lacrimal gland (TELG), often accompanied by acinar atrophy and secretory ducts dilatation. Immunohistochemistry revealed parasitism in all samples, in different intensities.

【 授权许可】

Unknown