Post-liver transplantation immonusuppression: main principles and modern implementation

Ķazaķstannyṇ Klinikalyķ Medicinasy

Zhanat Spatayev¹  Kakharman Yesmembetov²  Kulpash Kaliaskarova² 

[1] Department of Hepatobiliary Surgery and Liver Transplantation, National Scientific Center for Oncology and Transplantology, University Medical Center, Astana, Republic of Kazakhstan;Department of Hepatology, Republican Diagnostic Сenter, University Medical Center, Astana, Republic of Kazakhstan;

关键词: liver transplantation;    immunosuppression;    liver cirrhosis;    tacrolimus;    mycophenolic acid;   

DOI  :  10.23950/1812-2892-JCMK-00340

来源: DOAJ

【 摘 要 】

Liver transplantation is the only radical treatment option for the patients with end-stage liver disease. Immunosuppressive therapy is essential for survival of the liver graft and the recipient. There are several tactics of immunosuppression, majority of them utilising tacrolimus as the mainstay. Prolonged use of immunosuppressive drugs is associated with serious adverse effects. Thus, majority of the transplant-centers use combination of several immunosuppressive agents in order to minimise risk and effects of adverse events.

【 授权许可】

Unknown