In Situ Characterization of Polycaprolactone Fiber Response to Quasi-Static Tensile Loading in Scanning Electron Microscopy

Polymers

Daniel Hülsbusch¹  Frank Walther¹  Ronja Scholz¹  Alexander Delp¹  Birgit Glasmacher²  Alexander Becker²  Marc Müller² 

[1] Department of Materials Test Engineering (WPT), TU Dortmund University, 44227 Dortmund, Germany;Institute for Multiphase Processes, Leibniz University Hannover, 30823 Garbsen, Germany;

关键词: in situ tensile testing;    scanning electron microscopy;    microstructure;    damage mechanisms;    tissue engineering;    electrospinning;   

DOI  :  10.3390/polym13132090

来源: DOAJ

【 摘 要 】

Microstructural responses to the mechanical load of polymers used in tissue engineering is notably important for qualification at in vivo testing, although insufficiently studied, especially regarding promising polycaprolactone (PCL). For further investigations, electrospun PCL scaffolds with different degrees of fiber alignment were produced, using two discrete relative drum collector velocities. Development and preparation of an adjusted sample geometry enabled in situ tensile testing in scanning electron microscopy. By analyzing the microstructure and the use of selected tracking techniques, it was possible to visualize and quantify fiber/fiber area displacements as well as local fractures of single PCL fibers, considering quasi-static tensile load and fiber alignment. The possibility of displacement determination using in situ scanning electron microscopy techniques for testing fibrous PCL scaffolds was introduced and quantified.

【 授权许可】

Unknown