Regulatory Synchronization of Hemodynamics of the Heart and Brain in Norm

International Journal of Biomedicine

Valery Utkin¹  Andrey Kruglov¹  Alexander Vasilyev²  Alexander Kruglov² 

[1] Moscow, the Russian Federation;Central Research Institute of Radiation Diagnosis;

关键词: cardiac cycle;    hemodynamic parameters;    cardio-cerebral synchronization;    ecg;   

DOI  :  10.21103/Article9(4)_OA1

来源: DOAJ

【 摘 要 】

By catheterization, the integral indicators of synchronization and interaction of blood flows, designated as “venous and arterial boluses,” were obtained, studied and analyzed in healthy people on the pathway: right heart–lung–left heart. It has been confirmed that the complete CC of the BB from RA to the ejection from the LV has a length equal to two completed heart contraction cycles. Interaction of venous and arterial boluses, with differentiated external myocardial exposure, along the path “venous block of the heart–lung–arterial block of the heart,” forms averaged (compensated by the flexible septum) variable pressure values between the stages of intracardiac routes of BBs (unidirectional, synchronous, but spread in the space). The complex of these pressure values creates an intracardiac pressure balance at the border of high- and low-energy processes of the heart. We defined the sequential dynamics of these values as CMIP. Our mathematical and graphical data demonstrate the presence of direct and inversecardio-cerebral wave connections, where the waveguides are the vessels of entry and exit from the skull. We believe that CMIP is a universal, central rhythmic process, a regulator that determines the sequence and intensity of the CC phases, HR, and synchronous nervous and wave effects on brain structures. The modulating effect of CMIP on brain structures, providing some sensory-motor reactions, behavioral functions and forms of behavior, occurs outside the realm of consciousness. Our data suggest that the modulating effect of CMIP on the brain is carried out not only along the neural pathways, but also by the vascular wave structures that combine the heart and brain into a single hydrodynamic structure with phase-varying volume and configuration, as well as variable patterns of regulatory impulses.

【 授权许可】

Unknown