Association of Total and Trimester-Specific Gestational Weight Gain Rate with Early Infancy Weight Status: A Prospective Birth Cohort Study in China

Nutrients

Ning Ding¹  Yanan Ma²  Ming Gao³  Jiajin Hu³  Xiaotong Wei³  Deliang Wen³  Emily Oken⁴  IzzuddinM. Aris⁴ 

[1] Department of Curriculum and Teaching Research, Research Center of Medical Education, China Medical University, Shenyang 110122, Liaoning, China;Department of Epidemiology and Health Statistics, School of Public Health, China Medical University, Shenyang 110122, Liaoning, China;Department of Social Medicine, School of Public Health, China Medical University, Shenyang 110122, Liaoning, China;Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, Boston, MA 02215, USA;

关键词: gestation weight gain;    trimester-specific;    infancy;    weight status;    body mass index;   

DOI  :  10.3390/nu11020280

来源: DOAJ

【 摘 要 】

Studies to examine the associations of gestational weight gain (GWG) with offspring weight status during infancy are needed, especially among Asian populations. We examined 801 mother⁻infant pairs from a prospective cohort study in China to assess the associations of total and trimester-specific GWG with early infant weight status. We used linear mixed effects models and linear regression models to examine the longitudinal and time-point associations of GWG rate (kg/week) with infant growth measures (z-scores of body-mass-index (BMIZ), weight-for-age (WFAZ) and length-for-age (LFAZ)) at birth, 1, 3, and 6 months. Greater total GWG rate was associated with higher BMIZ (β:1.34 SD units (95% CI: 0.84, 1.83) per 1 kg/week increase in GWG) and higher WFAZ (β:1.18 SD units (95% CI: 1.01, 2.28)) across the first 6 months of life. GWG rate in the first two trimesters but not in the third trimester was positively associated with infant BMIZ. The association between GWG rate and infant BMIZ was significant at all timepoints and more pronounced in normal weight women and among male infants. In conclusion, greater GWG rate is positively associated with offspring BMIZ in the first 6 months of life, the association is mostly driven by GWG in the first two trimesters.

【 授权许可】

Unknown