A 12-Year Retrospective Study of Invasive Amoebiasis in Western Sydney: Evidence of Local Acquisition

Tropical Medicine and Infectious Disease

Chandra Adhikari¹  Ana Domazetovska²  Shobini Sivagnanam²  Nicole Gilroy³  Matthew Watts³  Damien Stark⁴  Rogan Lee⁵ 

[1] Department of Anatomical Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead NSW 2145, Australia;Department of Infectious Diseases, Blacktown Hospital, Blacktown NSW 2148, Australia;Department of Infectious Diseases, Westmead Hospital, Westmead NSW 2145, Australia;Department of Microbiology, St. Vincent’s Hospital, Darlinghurst NSW 2010, Australia;New South Wales Health Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead NSW 2145, Australia;

关键词: amoebiasis;    Entamoeba histolytica;    endemic;    local acquisition;    colitis;    liver abscess;   

DOI  :  10.3390/tropicalmed3030073

来源: DOAJ

【 摘 要 】

In Australia, amoebiasis is thought to occur in travellers, immigrants from endemic areas, and among men who have sex with men. Prevalence of amoebiasis in communities with immigrants from Entamoeba histolytica-endemic countries is unknown. The present study is a retrospective case series analysis of patients with laboratory-confirmed amoebiasis from Western Sydney Local Health District, Australia, between years 2005 and 2016. Forty-nine patients with amoebiasis were identified, resulting in an estimated annual incidence of up to 1.1 cases per 100,000 adults. Many were born in Australia (15/47) and India (12/47). Three patients (3/37) had no history of overseas travel, two others had not travelled to an endemic country, and an additional two had a very remote history of overseas travel; one died of fulminant amoebic colitis. Three patients (3/16) were employed in the food industry and one had a history of colonic irrigation in an Australian ‘wellness clinic’. Patients had invasive amoebiasis with either liver abscess (41/48) or colitis (7/48), diagnosed most commonly by serology. Invasive procedures were common, including aspiration of liver abscess (28/41), colonoscopy (11/49), and partial hepatectomy (1/49). Although rare, local acquisition of amoebiasis occurs in Western Sydney and contributes to significant morbidity and hospital admissions.

【 授权许可】

Unknown