Magnetic resonance imaging spectrum of perinatal hypoxic–ischemic brain injury

Indian Journal of Radiology and Imaging

V K Sreenivasan¹  Rose Xavier²  V C Manoj²  M K Aneesh³  P S Priya³  Ashok Kumar³  Binoj Varghese³ 

[1] Department of Paediatrics, Amala Institute of Medical Sciences, Thrissur, Kerala, India;Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India;Department of Radiology, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India;

关键词: cortical highlighting;    germinal matrix hemorrhage;    hypoxic ischemic encephalopathy;    hypoxic ischemic injury;    periventricular leukomalacia;   

DOI  :  10.4103/0971-3026.190421

来源: DOAJ

【 摘 要 】

Perinatal hypoxic–ischemic brain injury results in neonatal hypoxic–ischemic encephalopathy and serious long-term neurodevelopmental sequelae. Magnetic resonance imaging (MRI) of the brain is an ideal and safe imaging modality for suspected hypoxic–ischemic injury. The pattern of injury depends on brain maturity at the time of insult, severity of hypotension, and duration of insult. Time of imaging after the insult influences the imaging findings. Mild to moderate hypoperfusion results in germinal mazatrix hemorrhages and periventricular leukomalacia in preterm neonates and parasagittal watershed territory infarcts in full-term neonates. Severe insult preferentially damages the deep gray matter in both term and preterm infants. However, associated frequent perirolandic injury is seen in term neonates. MRI is useful in establishing the clinical diagnosis, assessing the severity of injury, and thereby prognosticating the outcome. Familiarity with imaging spectrum and insight into factors affecting the injury will enlighten the radiologist to provide an appropriate diagnosis.

【 授权许可】

Unknown