Association of Dietary Fatty Acid Consumption Patterns with Risk of Hyper-LDL Cholesterolemiain Korean Adults

Nutrients

Eunhee Choi¹  Seoeun Ahn¹  Hyojee Joung¹ 

[1] Department of Public Health Science, Graduate School of Public Health, Seoul National University,Seoul 08826, Korea;

关键词: dietary fatty acids;    hyper-LDL cholesterolemia;    Korean Genome and Epidemiology Study (KoGES);    cohort study;   

DOI  :  10.3390/nu12051412

来源: DOAJ

【 摘 要 】

This study aimed to identify the association between the risk of hyper-LDL cholesterolemia (hyper-LDLC) and fatty acid consumption patterns (FACPs) using the data from the Korean Genome and Epidemiology Study (KoGES) prospective cohort. A total of 6542 middle-aged Korean adults were included in the analysis. Four FACPs were identified through principal component analysis of the reported intakes of 34 fatty acids (FAs): “long-chain FA pattern”; “short & medium-chain saturated fatty acid (SFA) pattern”; “n-3 polyunsaturated fatty acid (PUFA) pattern”; and “long-chain SFA pattern”. The “long-chain SFA pattern” lowered the risk of hyper-LDLC (relative risk (RR), 0.82; 95% confidence interval (CI), 0.72–0.94; p for trend, 0.004) and the “short & medium-chain SFA pattern” increased the risk of hyper-LDLC (RR, 1.17; 95% CI, 1.03–1.32; p for trend = 0.004). In sex-stratified analyses, the associations of the “long-chain SFA pattern” (RR, 0.73; 95% CI, 0.58–0.93; p for trend = 0.007) and the “short & medium-chain SFA pattern” (RR, 1.34; 95% CI, 1.07–1.69; p for trend = 0.003) with the hyper-LDLC risk were observed only in men, but not in women. These results suggest that FACPs with a high intake of long-chain SFA or a low intake of short and medium-chain SFA may protect Korean adults from hyper-LDLC.

【 授权许可】

Unknown