VLCKD in Combination with Physical Exercise Preserves Skeletal Muscle Mass in Sarcopenic Obesity after Severe COVID-19 Disease: A Case Report

Healthcare

Lucio Gnessi¹  Sabrina Basciani¹  Alessandra Feraco²  Andrea Armani²  Massimiliano Caprio²  Luigi Barrea³  Elisabetta Camajani⁴ 

[1] Department of Experimental Medicine, University of Rome “La Sapienza”, 00161 Rome, Italy;Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy;Endocrinology Unit, Department of Clinical Medicine and Surgery, University Federico II, 80131 Naples, Italy;PhD Program in Endocrinological Sciences, University of Rome “La Sapienza”, 00161 Rome, Italy;

关键词: physical training;    ketogenic diet;    SARS-CoV-2;    ketone bodies;    obesity;    sarcopenia;   

DOI  :  10.3390/healthcare10030573

来源: DOAJ

【 摘 要 】

The prevalence of sarcopenic obesity is increasing worldwide, with a strong impact on public health and the national health care system. Sarcopenic obesity consists of fat depot expansion and associated systemic low-grade inflammation, exacerbating the decline in skeletal muscle mass and strength. Dietary approach and physical exercise represent essential tools for reducing body weight and preserving muscle mass and function in subjects with sarcopenic obesity. This case report describes the effects of a dietary intervention, based on a Very-Low-Calorie Ketogenic Diet (VLCKD) combined with physical exercise, on body composition, cardiometabolic risk factors, and muscle strength in a woman with sarcopenic obesity, two weeks after hospitalization for bilateral interstitial pneumonia due to COVID-19. To our knowledge, this is the first case report to describe the efficacy of a combined approach intervention including VLCKD along with physical exercise, in reducing fat mass, improving metabolic profile, and preserving skeletal muscle performance in a patient with obesity, soon after severe COVID-19 disease.

【 授权许可】

Unknown