Molecules | |
Insecticidal Constituents and Activity of Alkaloids from Cynanchum mongolicum | |
Yiqing Liu1  Pingping Liu2  Yang Ge2  Wangpeng Shi2  Liu Zhang2  Hongxing Chen2  Ibrahima Camara2  Rui Yang2  | |
[1] Collaborative Innovation Center of Special Plant Industry, Chongqing University of Arts and Sciences, Chongqing 402160, China;College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China; | |
关键词: Cynanchum mongolicum; alkaloids; insecticidal constituents; insecticidal activity; Spodoptera litura; Lipaphis erysimi; | |
DOI : 10.3390/molecules200917483 | |
来源: DOAJ |
【 摘 要 】
Based on MS and NMR data and bioassay-guided tracing, three insecticidal alkaloids I, II and III from Cynanchum mongolicum were identified to be antofine N-oxide, antofine and tylophorine. Alkaloid I was more toxic than alkaloids II and III, but they were less active against Spodoptera litura than total alkaloids. The contact toxicity from these alkaloids against the aphid Lipaphis erysimi was significant, as the 24 h-LC50 values of alkaloids I, II, III and total alkaloids were 292.48, 367.21, 487.791 and 163.52 mg/L, respectively. The development disruption of S. litura larvae was tested, the pupation and emergence rates of S. litura decreased and the acute mortality of S. litura increased significantly by day 3 after being injected in their body cavity with 10–40 mg/L of total alkaloid. The ecdysone titer of treated S. litura larvae and prepupae declined with increasing alkaloid concentration. The alkaloids of Cynanchum mongolicum are potential insect growth inhibitors.
【 授权许可】
Unknown