The Efficacy of Intraoperative Passive Language Mapping for Glioma Surgery: A Case Report

Frontiers in Neurology

Sumio Kobayashi¹  Takafumi Kiuchi¹  Kohei Kanaya¹  Takumi Mitsuhashi² 

[1] Department of Neurosurgery, Iida Municipal Hospital, Nagano, Japan;Department of Neurosurgery, Juntendo University, Tokyo, Japan;Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan;

关键词: cortiq;    awake craniotomy;    intraoperative passive language mapping;    real-time;    high-gamma activity;    glioma;   

DOI  :  10.3389/fneur.2021.652401

来源: DOAJ

【 摘 要 】

Background: Recently, electrocorticographic (ECoG) studies have emphasized the importance of gamma band-based functional mapping in the presurgical localization of the eloquent cortex. Passive functional mapping using ECoG signals provides a reliable method for identifying receptive language areas without many of the risks and limitations associated with electrical cortical stimulation. We report a surgical case of left temporal malignant glioma with intraoperative passive language mapping.Case Description: A 78-year-old woman was diagnosed with left temporal glioma with inspection of her language difficulty. MRI showed a left temporal tumor measuring 74.6 × 50.0 × 51.5 mm in size. Real-time CortiQ-based mapping using high-gamma activity by word-listening and story-listening tasks was performed. Significant listening task-evoked high gamma activities were detected in 5 channels in the superior temporal gyrus and one channel in the middle temporal gyrus. The tumor was grossly removed except for the region corresponding to listening task-evoked high gamma activities. Postoperatively, the patient's symptoms of language comprehension difficulty improved, and no new neurological deficits were observed.Conclusion: Intraoperative passive language mapping was successfully performed, and the patient's language function was well-preserved. Intraoperative passive language mapping, which is applicable in a short time and under general anesthesia, can be an important tool for detecting language areas.

【 授权许可】

Unknown