Influence of monomer and crosslinker molar ratio on the swelling behaviour of thermosensitive hydrogels

Chemical Industry and Chemical Engineering Quarterly

关键词: thermosensitive hydrogel;    residual monomers;    swelling;    Nisopropylacrylamide;    2-hydroxypropyl-methacrylate;   

DOI  :  10.2298/CICEQ110711040I

来源: DOAJ

【 摘 要 】

The synthesis of thepoly(N-isopropylacrylamide-co-2-hydroxypropylmethacrylate) hydrogel alongwith the analysis of the residual monomers content and influence of monomerand crosslinker molar ratios on the swelling behaviour was investigated.Synthesis of thermosensitive hydrogel based on N-isopropylacrylamide wascarried out with the molar ratios of 5, 10, 15 and 20 mol. % of monomer 2-hydroxypropyl-methacrylate, in the presence of ethylene glycol dimethacrylateas a crosslinker (1, 1.5, 2 and 3 mol. %) and2,2'-azobis(2-methylpropionitril) as an initiator in acetone. The quantitiesof residual monomers in the synthesized copolymers were determined by HPLCmethod, ranging from 0.19 to 0.49 % for N-isopropylacrylamide and from 0.13to 0.63 % for 2-hydroxypropyl-methacrylate, counting the amount of xerogel.The hydrogels swelling ratio depending on time at 20 and 40°C was examined.It was found that hydrogel with 5 mol. % 2-hydroxypropyl-methacrylate and 1mol. % ethylene glycol dimethacrylate had the highest degree of swelling (α =29.59) at 20°C, and that hydrogel with 20 mol. % 2-hydroxypropyl-methacrylateand 3 mol. % ethylene glycol dimethacrylate had the lowest swelling degree (α= 2.17) at 40°C.

【 授权许可】

Unknown