Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

Molecules

WamidhH. Talib¹  AsmaIsmail Mahmod¹  Safa Daoud²  ReemFawaz Abutayeh²  Izzeddin Alsalahat² 

[1] Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman 11931, Jordan;Department of Pharmaceutical Chemistry and Pharmacognosy, Applied Science Private University, Amman 11931, Jordan;

关键词: alternative anticancer therapies;    natural products;    plant extracts;    curcumin;    thymoquinon;   

DOI  :  10.3390/molecules25225319

来源: DOAJ

【 摘 要 】

Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a priority. In this review, we describe the main plant-derived natural products used as anticancer agents. Natural sources, extraction methods, anticancer mechanisms, clinical studies, and pharmaceutical formulation are discussed in this review. Studies covered by this review should provide a solid foundation for researchers and physicians to enhance basic and clinical research on developing alternative anticancer therapies.

【 授权许可】

Unknown