Implementation of Industrial Additive Manufacturing: Intelligent Implants and Drug Delivery Systems

Journal of Functional Biomaterials

Roy Björkstrand¹  Mika Salmi¹  JanSher Akmal¹  Jouni Partanen¹  Antti Mäkitie² 

[1] Department of Mechanical Engineering, Aalto University, 02150 Espoo, Finland;Department of Otorhinolaryngology–Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, 00029 Helsinki, Finland;

关键词: additive manufacturing;    3D printing;    biomaterials;    parametric modeling;    drug delivery systems;    embedding;    medicine;    radiofrequency identification;    object memory;    internet of things;   

DOI  :  10.3390/jfb9030041

来源: DOAJ

【 摘 要 】

The purpose of this study is to demonstrate the ability of additive manufacturing, also known as 3D printing, to produce effective drug delivery devices and implants that are both identifiable, as well as traceable. Drug delivery devices can potentially be used for drug release in the direct vicinity of target tissues or the selected medication route in a patient-specific manner as required. The identification and traceability of additively manufactured implants can be administered through radiofrequency identification systems. The focus of this study is to explore how embedded medication and sensors can be added in different additive manufacturing processes. The concept is extended to biomaterials with the help of the literature. As a result of this study, a patient-specific drug delivery device can be custom-designed and additively manufactured in the form of an implant that can identify, trace, and dispense a drug to the vicinity of a selected target tissue as a patient-specific function of time for bodily treatment and restoration.

【 授权许可】

Unknown