Blood serum protein status in broilers fed with increasing concentrations of ochratoxin A

Acta Veterinaria

关键词: A/G ratio;    broiler;    ochratoxin A;    poultry;    proteins;   

DOI  :  10.2298/AVB1301077N

来源: DOAJ

【 摘 要 】

The 42-day long study was performed on a total number of 48 Hybro broilersdivided into four groups. After the pre-experimental period of 14 days, 3experimental groups of broilers (n=12) were formed and fed diets thatcontained 0.5, 1.0 and 1.5 mg/kg ochratoxin A (OTA) during the next sevenconsecutive days. In the same period, the control group of broilers was fed adiet with no toxin added. After the period of toxin addition, blood sampleswere taken from 6 animals in each group. The remaining animals (n=6) from thecontrol and experimental groups were fed diets without OTA until the 42nd dayof the study, when the blood samples were taken again. The total level ofblood serum proteins was affected by treatment with different doses of OTA,but a significant and dose dependent increase of albumins together with adecrease of γ-globulin fraction was established. A/G ratio(Albumine/Globuline) suggested that the globulins were the dominant proteinfraction in the blood serum samples obtained from all the broilers includedin this study. The concentrations of α- and β- globulin in the serum werewithin physiological limits, but the concentration of γ-globulinssignificantly decreased. It can be concluded that the increasing dietary OTAlevels (0.5, 1.0 and 1.5 mg/kg) had dose-dependent cumulative effect on bloodserum proteins status in broilers, and the effect lasts even after thewithdrawal of OTA from the feed.

【 授权许可】

Unknown