Unicompartmental Knee Replacement in Obese Patients: A Systematic Review and Meta-Analysis

Journal of Clinical Medicine

Biagio Zampogna¹  Vincenzo Denaro¹  Stefano Campi¹  Erika Albo¹  Giuseppe Francesco Papalia¹  Carlo Esposito¹  Rocco Papalia¹  Francesca Cannata² 

[1] Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy;Unit of Endocrinology and Diabetes, Department of Medicine, Campus Bio-Medico University of Rome, 00128 Rome, Italy;

关键词: unicompartmental knee replacement;    obesity;    body mass index;    revisions;    infections;   

DOI  :  10.3390/jcm10163594

来源: DOAJ

【 摘 要 】

Thanks to modern surgical techniques and implants, traditional exclusion criteria for unicompartmental knee arthroplasty (UKA) are no longer considered contraindications. The aim of this study is to clarify the impact of obesity on functional outcomes and revision rates of UKA. We performed a comprehensive systematic review using PubMed–Medline, Google Scholar and Cochrane Central. Then, we extracted data related to body mass index (BMI), age and follow-up, functional outcome scores and rate of revisions (all-cause, aseptic and septic). Patients were stratified according to BMI into two groups: non-obese (BMI < 30) and obese (BMI ≥ 30). We identified 22 eligible studies, of which 13 were included in the meta-analysis. Patients with a BMI > 30 had a significantly higher likelihood for revision (p = 0.02), while the risk of septic revision was similar (p = 0.79). The clinical outcome measures showed a significant difference in favor of patients with a BMI < 30 (p < 0.0001). The improvements in Oxford Knee Score and Knee Society Score were significant in both obese and non-obese patients, although the latter showed inferior results. The results of this systematic review and meta-analysis show that BMI is not a contraindication to UKA. However, obese patients have a higher risk for aseptic failure and lower improvement in clinical scores compared to non-obese patients.

【 授权许可】

Unknown