Acute and sub-chronic toxicity study of recombinant bovine interferon alpha in rodents

Journal of Veterinary Research

Gao Dong-Mei¹  Yu Hai-Yang²  Wang Ming-Li²  Zhao Jun²  He Zhi-Yuan³  Wu Bo³  Zhou Wei³  Xia Bing-Bing³  Jiang Min-Zhi³ 

[1] Department of Clinical Laboratory, Third Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, 230032, P.R. China;Department of Microbiology, Anhui Medical University, Hefei, Anhui Province, 230032, P.R. China;Wuhu Interferon Bio-products Industry Research Institute Co., Ltd, Wuhu, Anhui Province, 241007, P.R. China;

关键词: recombinant bovine interferon-alpha (rboifn-α);    acute toxicity;    sub-chronic toxicity;    pathology;    rat;   

DOI  :  10.2478/jvetres-2021-0023

来源: DOAJ

【 摘 要 】

Recombinant bovine interferon alpha (rBoIFN-α) has been demonstrated to have antiviral activity. However, no conduct of acute or chronic toxicity tests has been reported.

【 授权许可】

Unknown