Recent Advances in the Synthesis and Biomedical Applications of Nanocomposite Hydrogels

Pharmaceutics

Orazio Vittorio¹  Tania Spataro²  Nevio Picci²  Umile Gianfranco Spizzirri²  Fiore Pasquale Nicoletta²  Manuela Curcio²  Giuseppe Cirillo²  Francesca Iemma²  Silke Hampel³ 

[1] Children’s Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales, Sydney, 2052, Australia;Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036 Rende, Italy;Leibniz Institute for Solid State and Materials Research, PF 270116, D-01171 Dresden, Germany;

关键词: carbon nanotubes;    graphene;    composite hydrogels;    electro-responsive;   

DOI  :  10.3390/pharmaceutics7040413

来源: DOAJ

【 摘 要 】

Hydrogels sensitive to electric current are usually made of polyelectrolytes and undergo erosion, swelling, de-swelling or bending in the presence of an applied electric field. The electrical conductivity of many polymeric materials used for the fabrication of biomedical devices is not high enough to achieve an effective modulation of the functional properties, and thus, the incorporation of conducting materials (e.g., carbon nanotubes and nanographene oxide) was proposed as a valuable approach to overcome this limitation.By coupling the biological and chemical features of both natural and synthetic polymers with the favourable properties of carbon nanostructures (e.g., cellular uptake, electromagnetic and magnetic behaviour), it is possible to produce highly versatile and effective nanocomposite materials. In the present review, the recent advances in the synthesis and biomedical applications of electro-responsive nanocomposite hydrogelsare discussed.

【 授权许可】

Unknown