期刊论文详细信息
OncoImmunology
Metabolism in the tumor microenvironment: insights from single-cell analysis
Zhengtao Xiao1  Ziwei Dai1  Jason W. Locasale2 
[1] Duke University School of Medicine;Mainline Station Drive;
关键词: cancer metabolism;    immunometabolism;    tumor microenvironment;    single-cell rna sequencing;   
DOI  :  10.1080/2162402X.2020.1726556
来源: DOAJ
【 摘 要 】

The metabolism of both cancer and immune cells in the tumor microenvironment (TME) is poorly understood since most studies have focused on analysis in bulk samples and ex vivo cell culture models. Our recent analyses of single-cell RNA sequencing data suggest that the metabolic features of single cells within TME differ greatly from those of the bulk measurements. Here, we discuss some key findings about metabolism in cancer and immune cells and discuss possible relevance to immunotherapy.

【 授权许可】

Unknown   

  文献评价指标  
  下载次数:0次 浏览次数:0次