Cardiometabolic Health in Relation to Lifestyle and Body Weight Changes 3–8 Years Earlier

Nutrients

TessaJ. Roseboom¹  Henk Groen²  Annemieke Hoek³  ReinoudJ. B. J. Gemke⁴  Mireille.N. M. Van Poppel⁴  TessaM. Van Elten⁴  BenW. Mol⁵ 

[1] Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam UMC, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;Department of Epidemiology, University of Groningen, University Medical Centre Groningen, 9700 RB Groningen, The Netherlands;Department of Obstetrics and Gynecology, University of Groningen, University Medical Centre, Groningen, 9700 RB Groningen, The Netherlands;Department of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan, 1117 Amsterdam, The Netherlands;School of Medicine, The Robinson Institute, University of Adelaide, 5006 Adelaide, Australia;

关键词: dietary intake;    physical activity;    body weight;    lifestyle change;    cardiometabolic health;    long-term follow-up;   

DOI  :  10.3390/nu10121953

来源: DOAJ

【 摘 要 】

The degree to which individuals change their lifestyle in response to interventions differs and this variation could affect cardiometabolic health. We examined if changes in dietary intake, physical activity and weight of obese infertile women during the first six months of the LIFEstyle trial were associated with cardiometabolic health 3⁻8 years later (N = 50⁻78). Lifestyle was assessed using questionnaires and weight was measured at baseline, 3 and 6 months after randomization. BMI, blood pressure, body composition, pulse wave velocity, glycemic parameters and lipid profile were assessed 3⁻8 years after randomization. Decreases in savory and sweet snack intake were associated with lower HOMA-IR 3⁻8 years later, but these associations disappeared after adjustment for current lifestyle. No other associations between changes in lifestyle or body weight during the first six months after randomization with cardiovascular health 3⁻8 years later were observed. In conclusion, reductions in snack intake were associated with reduced insulin resistance 3⁻8 years later, but adjustment for current lifestyle reduced these associations. This indicates that changing lifestyle is an important first step, but maintaining this change is needed for improving cardiometabolic health in the long-term.

【 授权许可】

Unknown