Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings

Micromachines

Wen-Jin Cherng¹  Chi-Hsiao Yeh¹  Chau-Chang Chou²  Yu-Heng Pan²  Zuo-Syuan Dong² 

[1] College of Medicine, Chang Gung University, Taoyuan City 33302, Taiwan;Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung 20224, Taiwan;

关键词: mechanical heart valve;    computational fluid dynamics;    degradation;    biomedical coatings;   

DOI  :  10.3390/mi8040132

来源: DOAJ

【 摘 要 】

Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of understanding with regards to the shaker’s rotating conditions and the corresponding physiological condition. This study implemented numerical simulations by establishing a fluid dynamic model to evaluate the intensity of the shear stress under various rotating speeds and diameters of the shaker. The results are valuable to conduct in vitro tests for estimating the performance of biomedical coatings under real hemodynamic conditions and can be applied to other fluid-contact implants.

【 授权许可】

Unknown