Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review

Kaohsiung Journal of Medical Sciences

周岳弘¹  Yueh-Hung Chou¹  王馨儀²  Hsin-Yi Wang²  謝明書³  Min-Shu Hsieh³ 

[1] Department of Anatomical Pathology, Far Eastern Memorial Hospital, Taipei, Taiwan;Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan;Department of Pathology, National Taiwan University Hospital Yun-Lin Branch, Taiwan;

关键词: Gastrointestinal injury;    Ischemic enterocolitis;    Kayexalate;    Sodium polystyrene sulfonate;    Sorbitol;   

DOI  :  10.1016/j.kjms.2010.12.010

来源: DOAJ

【 摘 要 】

Kayexalate (sodium polystyrene sulfonate) is a cation-exchange resin used to treat patients with hyperkalemia. Concomitant administration of kayexalate and sorbitol may induce gastrointestinal injury, which is potentially lethal. However, this well-documented complication is often underrecognized both clinically and pathologically. We propose a typical case along with colonoscopic photos and microscopic pictures. Additionally, we also present a review of the literature on this rare drug-induced side effect.

【 授权许可】

Unknown