Closed-loop neuromodulation will increase the utility of mouse models in Bioelectronic Medicine

Bioelectronic Medicine

Timir Datta-Chaudhuri¹ 

[1] Institute of Bioelectronic Medicine, The Feinstein Institutes for Medical Research, Northwell Health;

关键词: Bioelectronic medicine;    Implantable devices;    Neuromodulation;    Mouse model;    Preclinical research;    Engineering challenges;   

DOI  :  10.1186/s42234-021-00071-x

来源: DOAJ

【 摘 要 】

Abstract Mouse models have been of tremendous benefit to medical science for the better part of a century, yet bioelectronic medicine research using mice has been limited to mostly acute studies because of a lack of tools for chronic stimulation and sensing. A wireless neuromodulation platform small enough for implantation in mice will significantly increase the utility of mouse models in bioelectronic medicine. This perspective examines the necessary functionality of such a system and the technical challenges needed to be overcome for its development. Recent progress is examined and the outlook for the future of implantable devices for mice is discussed.

【 授权许可】

Unknown