期刊论文详细信息
Journal of the Serbian Chemical Society | |
New S-alkylated 1,2,4-triazoles incorporating diphenyl sulfone moieties with potential antibacterial activity | |
关键词: alkylation; 1; 2; 4-triazole-3-thione; antibacterial activity; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
Alkylation of the 5-{4-[(4-bromophenyl)sulfonyl]phenyl}-4-(3/4-me¬thylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones 3a,b with various alkylation agents, i.e., ethyl bromide, phenacyl bromide and ethyl chloroacetate, afforded the S-substituted 1,2,4-triazoles 4-6a,b. The structures of these new compounds were elucidated by elemental analysis and IR, UV, 1H-NMR, 13C-NMR and MS spectroscopy. The newly synthesized products were tested for their antibacterial effects.
【 授权许可】
Unknown