Acetate Metabolism in Anaerobes from the Domain Archaea

Life

James G. Ferry¹ 

[1] Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA;

关键词: methanogenesis;    fermentation;    respiration;    Methanosarcina;    Pyrococcus;    carbon monoxide;   

DOI  :  10.3390/life5021454

来源: DOAJ

【 摘 要 】

Acetate and acetyl-CoA play fundamental roles in all of biology, including anaerobic prokaryotes from the domains Bacteria and Archaea, which compose an estimated quarter of all living protoplasm in Earth’s biosphere. Anaerobes from the domain Archaea contribute to the global carbon cycle by metabolizing acetate as a growth substrate or product. They are components of anaerobic microbial food chains converting complex organic matter to methane, and many fix CO2 into cell material via synthesis of acetyl-CoA. They are found in a diversity of ecological habitats ranging from the digestive tracts of insects to deep-sea hydrothermal vents, and synthesize a plethora of novel enzymeswith biotechnological potential. Ecological investigations suggest that still moreacetate-metabolizing species with novel properties await discovery.

【 授权许可】

Unknown