Three New Isoprenylated Flavonoids from the Root Bark of Morus alba

Molecules

Dae-Young Lee¹  Daeseok Han²  Dong-Wook Lim²  Nam-In Baek³  Jae-Woo Jung³  Yeong-Geun Lee³  Ji-Hae Park³  Eun-Ji Oh³  Kyeong-Hwa Seo⁴ 

[1] Department of Herbal Crop Research, National Institute of Horticultural and Herbal Science, RDA, Eumseong 27709, Korea;Division of Metabolism and Functionality Research, Korea Food Research Institute, Sungnam 463-746, Korea;Graduate School of Biotechnology and Oriental Medicine Biotechnology, Kyung Hee University, Yongin 17104, Korea;Natural Medicine Research Center, KRIBB, Chengju 28116, Korea;

关键词: isoprenylated flavonoids;    Morus alba;    root bark;    sanggenon U;    sanggenon V;    sanggenon W;   

DOI  :  10.3390/molecules21091112

来源: DOAJ

【 摘 要 】

Phytochemical investigation of the root bark of Morus alba has led to the isolation and identification of three new isoprenylated flavonoids, namely sanggenon U (1), sanggenon V (2), and sanggenon W (3), along with four known isoprenylated flavonoids: euchrenone a7 (4), sanggenon J (5), kuwanon E (6), and kuwanon S (7). All compounds were isolated by repeated silica gel (SiO2), octadecyl SiO2 (ODS), and Sephadex LH-20 open column chromatography. The structure of the compounds were determined based on spectroscopic analyses, including nuclear magnetic resonance (NMR), mass spectrometry (MS), circular dichroism (CD), and infrared (IR). In addition, compounds 1–4 were isolated for the first time from the root bark of M. alba in this study.

【 授权许可】

Unknown