Case Report: Successful Management of Conidiobolus Lamprauges Rhinitis in a Dog

Frontiers in Veterinary Science

Maureen Jay¹  Jared A. Jaffey²  Nathan P. Wiederhold³  Eric T. Hostnik⁴  Aline Rodrigues Hoffman⁵  Sylvia H. Ferguson⁶ 

[1] Biomedical Sciences, Texas A&Department of Specialty Medicine, Midwestern University College of Veterinary Medicine, Glendale, AZ, United States;;Department of Surgery, Animal Medical &Department of Veterinary Clinical Sciences, Veterinary Medical Center, Ohio State University, Columbus, OH, United States;;Department of Veterinary Pathobiology, College of Veterinary Medicine &M University, College Station, TX, United States;

关键词: conidiobolomycosis;    fungal rhinitis;    canine (dog);    epistaxis;    itraconazole;    terbinafine;   

DOI  :  10.3389/fvets.2021.633695

来源: DOAJ

【 摘 要 】

This is a case of Conidiobolus lamprauges rhinitis in a Goldendoodle, that was presented for evaluation of sneezing, coughing, lethargy, as well as right-sided epistaxis and clear ocular discharge. Computed tomography revealed a large amount of soft tissue within the right nasal passage that obscured the osseous turbinates from the right maxillary canine tooth to the right side of the choanae. Biopsies revealed eosinophilic granulomas with variable number of basophilic to negatively staining, septate, fungal hyphae with non-parallel walls and irregular branching that were subsequently determined to be Conidiobolus lamprauges via panfungal PCR and sequencing. Complete and sustained resolution of clinical disease was achieved after 75 days of systemic antifungal therapy. This report describes for the first time, important clinical features of a dog with nasal conidiobolomycosis that will facilitate its recognition, prognostication, and treatment in clinical practice.

【 授权许可】

Unknown