Erosive nappy erythema following sunitinib intake

The Pan African Medical Journal

Hassan Errihani¹  Saoussane Kharmoum¹ 

[1] Department of medical oncology, National institute of oncology, Rabat Morocco;

关键词: erosive;    erythema;    sunitinib;    antiangiogenic drug;   

DOI  :  10.11604/pamj.2013.14.46.2235

来源: DOAJ

【 摘 要 】

We report on the case of a 54 years old man treating for a metastatic renal carcinoma who had experienced a dermatological toxicity referring to sunitinb intake. The antiangiogenic drug was delivered at a daily dose of 50mg for 4 weeks followed by two weeks of rest. By the second week of treatment the patient presented a nappy erythema evolving towards erosive lesions bleeding at mild friction and extending to the perianal and scrotal area, the process fulfilled the maximal intensity at 4 weeks and improved after the discontinuation of sunitinib. The patient refused the reintroduction of the drug. No skin biopsy was developed seeing that the lesions disappeared 4 weeks later.

【 授权许可】

Unknown