First Report of a Severe Outbreak of Aujeszky’s Disease in Cattle in Sicily (Italy)

Pathogens

Elena Colombino¹  MariaTeresa Capucchio¹  LuciaRita Maria Gibelli²  Michele Fiasconaro³  CiarelloFlavia Pruiti³  Dorotea Ippolito³  Vincenzo Di Marco Lo Presti³  AnaMaria Moreno Martin⁴ 

[1] Department of Veterinary Sciences, University of Turin, Largo P. Braccini 2, 10095 Torino, Italy;Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna “B.Umbertini”, Via Bianchi 9, 25124 Brescia, Italy;Istituto Zooprofilattico Sperimentale “A.Mirri” della Sicilia, Via G. Marinuzzi 3, 90129 Palermo, Italy;National reference Centre for Aujeszky Disease-Istituto Zooprofilattico Sperimentale della Lombardia e dell’ Emilia Romagna “B.Umbertini”, Via Bianchi 9, 25124 Brescia, Italy;

关键词: cattle;    outbreak;    Aujeszky’s disease;    pseudorabies;    Suid Herpesvirus 1;    immunohistochemistry;   

DOI  :  10.3390/pathogens9110954

来源: DOAJ

【 摘 要 】

Aujeszky’s disease in cattle is caused by Suid herpes virus 1. The natural infection has been reported worldwide in bovine species and it is related to direct and indirect contact with infected pigs, which represent the main reservoir of the virus. Here, it is reported the first documented outbreak of Aujeszky’s disease in cattle in Sicily (Italy). Severe itching and nonspecific neurological symptoms were the main reported clinical signs. No characteristic gross and histological features were reported other than cutaneous lesions caused by excessive pruritus and hyperaemia, haemorrhages and inflammation in the central nervous system. Diagnosis was confirmed by real time PCR and immunohistochemistry on the nervous tissue. The route of infection remained unknown, but serological data observed in pigs living in close cohabitation with cattle revealed a circulation of a wild strain of the virus in the area. This study contributes to a better knowledge of this disease in a non-conventional host and suggests the need to increase the prophylaxis control plans in specific breeding contexts.

【 授权许可】

Unknown