Prevalence and Features of Thyroglossal Duct Cyst on Ultrasonography, According to Radioactive Iodine Therapy: A Single-Center Study

Frontiers in Endocrinology

Sung Ho Moon¹  Tae Kwun Ha²  Ha Kyoung Park²  Ji Sun Park³  Do Hun Kim⁴  Soo Jin Jung⁵  Ki Jung Ahn⁶  Hye Jung Choo⁷  Yoo Jin Lee⁷  Dong Wook Kim⁷  Gi Won Shin⁷  Jin Young Park⁷  Hye Jin Baek⁸ 

[1] Department of Anesthesiology and Pain Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of General Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Nuclear Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Otorhinolaryngology-Head and Neck Surgery, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Radiation Oncology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea;

关键词: thyroglossal duct cyst;    thyroidectomy;    radioactive iodine ablation;    ultrasonography;    prevalence;   

DOI  :  10.3389/fendo.2020.00188

来源: DOAJ

【 摘 要 】

Objective: The relationship between radioactive iodine therapy (RIT) and prevalence of thyroglossal duct cysts (TGDC) on ultrasonography (US) has not been reported. We assessed the prevalence and US features of TGDC according to RIT.Methods: From July 2017 to June 2018, 3,146 subjects underwent thyroid or neck US at our center. The presence or absence of TGDCs was prospectively investigated based on real-time US examination. Among the 3,146 subjects, 261 subjects were excluded because of <18 years of age, unclear information of RIT, or the presence of a radiation therapy history to the neck. Eventually, 2,885 subjects were included in this study.Results: Of the 2,885 subjects finally included, 126 (4.4%) showed a TGDC on US. Those with RIT history showed a higher prevalence of TGDCs than those without (no statistical difference, p = 0.062). In 697 male subjects, there were statistical differences in type of surgery, RIT history, and session number of RIT between those with or without TGDCs (p < 0.0001). In 126 subjects with TGDCs, only sex showed a significant difference between those with or without RIT history (p = 0.015). However, there were no significant differences in the location, size, and shape of TGDCs (p > 0.05). The common US features of TGDC were suprahyoid location, ~1 centimeter, and flat-to-ovoid or round shape.Conclusions: RIT may increase the prevalence of TGDCs, particularly in men.

【 授权许可】

Unknown