Pseudomembranous tracheitis caused by Aspergillus fumigatus in the setting of high grade T-cell lymphoma

Respiratory Medicine Case Reports

Prashant Malhotra, M.D.¹  Arunabh Talwar, M.D., FCCP²  Sonu Sahni, M.D.²  Karan Singh, MBBS²  Mina Makaryus, M.D.²  Paul Gill, B.S.² 

[1] Northwell Health, Department of Infectious Diseases, 400 Community Drive, Manhasset, NY 11030, United States;Northwell Health, Department of Pulmonary, Critical Care and Sleep Medicine, 410 Lakeville Rd., New Hyde Park, NY 11040, United States;

关键词: Pseudomembranous tracheitis;    Aspergillus;    Bronchoscopy;    Immunocompromised;    Chronic cough;    T-cell lymphoma;   

DOI  :  10.1016/j.rmcr.2017.03.016

来源: DOAJ

【 摘 要 】

Pseudomembranous tracheitis (PMT) is a rare condition most commonly caused by fungal or bacterial infection that is characterized by a pseudomembrane that partially or completely covers the tracheobronchial tree. PMT is most commonly found in immunocompromised patient populations, such as post-chemotherapy, AIDS, post-transplant and hematological malignancies. Due to its rarity, PMT is often not included in the differential diagnosis. This case describes a 65 year old male with persistent fever and refractory cough despite high dose empiric antibiotics. Subsequent bronchoscopy with biopsy revealed pseudomembranous tracheitis due to Aspergillus fumigatus in the setting of T-cell lymphoma. PMT should be considered in the differential diagnosis of refractory cough in the immunocompromised population. However, it has been described in patients with nonspecific respiratory symptoms such as dyspnea, cough, and other airway issues.

【 授权许可】

Unknown