Do Serum Vitamin D Levels Have Any Effect on Intrauterine Insemination Success?

International Journal of Fertility and Sterility

Ayla Sargin¹  Salim Erkaya¹  Ebru Ersoy¹  Aytekin Tokmak¹  A. Seval Ozgu-Erdinc¹  Nafiye Yilmaz¹  Halil Ibrahim Yakut² 

[1] Department of Obstetrics and Gynaecology, Zekai Tahir Burak Women’s Healthcare Training and Research Hospital,Ankara, Turkey;Zekai Tahir Burak Women’s Healthcare Training and Research Hospital, Ankara, Turkey;

关键词: infertility;    intrauterine insemination;    ovulation induction;    vitamin d;   

DOI  :  10.22074/ijfs.2018.5256

来源: DOAJ

【 摘 要 】

BackgroundRecent studies have shown that vitamin D has an essential role in the reproductive system. In thisstudy, we aimed to investigate the effect of vitamin D levels in patients undergoing ovulation induction (OI), andsubsequent intrauterine insemination (IUI) procedure.Materials and MethodsOne hundred and four infertile and one hundred and three fertile women were recruited inthis cross-sectional study which was conducted in a tertiary level maternity hospital. Infertile patients were dividedinto pregnant and non-pregnant subgroups after treatment. Individual characteristics and 25-hydroxyvitamin D3[25(OH) D3] levels were compared between the groups.ResultsThe vast majority of our study population consisted of women who had vitamin D deficiency (96.6%).There was no statistically significant difference between infertile and fertile groups in terms of serum 25 (OH) D3lev-els (P=0.512). Similarly, no significant difference was observed between the pregnant and non-pregnant subgroupsof infertile patients regarding 25 (OH) D3levels (P=0.267).ConclusionThere is no association between female infertility and serum vitamin D levels. Vitamin D does not pre-dict pregnancy in infertile women undergoing OI with IUI. Further research which will provide a comparison betweenmuch more women who have deficient and sufficient 25 (OH) D3levels is warranted.

【 授权许可】

Unknown