Polyurethane-Based Composites: Effects of Antibacterial Fillers on the Physical-Mechanical Behavior of Thermoplastic Polyurethanes

Polymers

Giovanna Bruni¹  Stefano Iervese²  Federico Bertoglio²  Livia Visai²  Maurizio Canetti³  Fabio Bertini³  Roberto Consonni³  Maurizio Villani³  Salvatore Iannace⁴ 

[1] Department of Chemistry, Physical Chemistry Section, University of Pavia, viale Taramelli 16, 27100 Pavia, Italy;Department of Molecular Medicine (DMM), Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Viale Taramelli 3/B, 27100 Pavia, Italy;Istituto di Scienze e Tecnologie Chimiche “Giulio Natta”—CNR, Via A. Corti 12, 20133 Milano, Italy;Istituto per i Polimeri, Compositi e Biomateriali—CNR, Piazzale Enrico Fermi 1, 80055 Portici (NA), Italy;

关键词: polymer matrix composites;    thermoplastic polyurethane (tpu);    titanium dioxide;    silver;    chitosan;    physical-mechanical properties;    antibacterial;   

DOI  :  10.3390/polym12020362

来源: DOAJ

【 摘 要 】

The challenge to manufacture medical devices with specific antibacterial functions, and the growing demand for systems able to limit bacterial resistance growth, necessitates the development of new technologies which can be easily produced at an industrial level. The object of this work was the study and the development of silver, titanium dioxide, and chitosan composites for the realization and/or implementation of biomedical devices. Thermoplastic elastomeric polyurethane was selected and used as matrix for the various antibacterial functions introduced during the processing phase (melt compounding). This strategy was employed to directly incorporate antimicrobial agents into the main constituent material of the devices themselves. With the exception of the composite filled with titanium dioxide, all of the other tested composites were shown to possess satisfactory mechanical properties. The best antibacterial effects were obtained with all the composites against Staphylococcus aureus: viability was efficiently inhibited by the prepared materials in four different bacterial culture concentrations.

【 授权许可】

Unknown