Generic therapy: the problem of choice

Кардиоваскулярная терапия и профилактика

S. N. Tolpygina¹ 

[1] State Research Centre for Preventive Medicine, Federal Agency on High Medical Technologies;

关键词: original and generic medications;    enalapril;    bioequivalence;    therapeutic equivalence;    comparative studies;   

DOI  :  

来源: DOAJ

【 摘 要 】

The main differences between original and generic medications are discussed, and the criteria necessary for official generic registration are presented. The author describes possible reasons for bioequivalence and therapeutic equivalence discrepancy between original and generic medications, with enalapril maleate as an example of such discrepancies. Methodological approaches to designing comparative studies on medication therapeutic equivalence are presented.

【 授权许可】

Unknown