BMC Genomics | |
Computational prediction and validation of C/D, H/ACA and Eh_U3 snoRNAs of |
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关键词:
U3 snoRNA;
Guide/ orphan snoRNAs;
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DOI : 10.1186/1471-2164-13-390 | |
来源: DOAJ |
【 摘 要 】
Abstract
Background
Small nucleolar RNAs are a highly conserved group of small RNAs found in eukaryotic cells. Genes encoding these RNAs are diversely located throughout the genome. They are functionally conserved, performing post transcriptional modification (methylation and pseudouridylation) of rRNA and other nuclear RNAs. They belong to two major categories: the C/D box and H/ACA box containing snoRNAs. U3 snoRNA is an exceptional member of C/D box snoRNAs and is involved in early processing of pre-rRNA. An antisense sequence is present in each snoRNA which guides the modification or processing of target RNA. However, some snoRNAs lack this sequence and often they are called orphan snoRNAs.
Results
We have searched snoRNAs of
Conclusion
Our results showed the presence of snoRNAs in
【 授权许可】
Unknown