Comorbidities and drug reactions in the elderly patient

Romanian Medical Journal

Camelia Cristina Diaconu¹  Laura Maria Condur¹  Ana Maria Alexandra Stănescu²  Oana Nicolescu³  Adriana Ticărău⁴  Mihaela Adela Iancu⁵  Dumitru Matei⁵  Cristina Mihaela Olariu⁵ 

[1] Cabinet medical individual, Bucureşti, România;Universitatea „Ovidius“, Constanţa, România;Cabinet medical individual, Bucureşti, România;Direcţia de Sănătate Publică Bucureşti;Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, România;

关键词: elderly;    ageing;    polipharmacy;   

DOI  :  10.37897/RMJ.2020.2.7

来源: DOAJ

【 摘 要 】

Aging is characterized by progressive and broadly predictable changes that are associated with increased susceptibility to many diseases. The process of prescribing medication is complex and includes: deciding whether a drug is indicated, choosing the best drug, determining a dose and an appropriate schedule for the patient's physiologic status, monitoring the effectiveness and toxicity, educating the patient about expected side effects, and indications for seeking consultation. More than half of adults over the age of 65 consulted in primary care use at least 5 medications. The risk of drug interactions and side effects is increased by augmenting the number of drugs used, as well as pharmacokinetic and pharmacodynamic changes. Applying the Beers criteria to elderly patients decreases the risk of drug interactions and side effects.

【 授权许可】

Unknown