Hemodynamic stability in total intravenous propofol anesthesia with midazolam coinduction versus general balanced anaesthesia in laparoscopic cholecystectomy

Vojnosanitetski Pregled

关键词: cholecystectomy, laparoscopic;    intraoperative period;    postoperative complications;    cardiovascular diseases;    anesthesia, general;   

DOI  :  10.2298/VSP1211967S

来源: DOAJ

【 摘 要 】

Background/Aim. Laparoscopic cholecystectomy can be a greater challenge foranesthesiologist than for surgeon if the patient is ASA III with concomitantcardiovascular diseases. The aim of our study was to compare the effect oftotal intravenous anesthesia (TIVA - propofol with midazolam) and generalbalanced anesthesia (GBA - midazolam, thiopenton, nitrous oxide and O2) onhemodynamic stability in the ASA III patients who underwent laparoscopiccholecystectomy. Methods. In our study, 60 patients were randomized into twogroups depending on whether they received TIVA or GBA. Heart rate, systolic,diastolic and mean arterial pressure were monitored continuously and recordedin five time intervals. Results. Statistical analysis showed that TIVA withpropofol provides better hemodynamic stability (less than 10% deviation frombasal values for each measured parameter) then GBA group (p < 0.01).Conclusion. Total intravenous anesthesia with propofol provides betterhemodynamic stability for ASA III patients with concomitant cardiovasculardiseases then GBA.

【 授权许可】

Unknown