Methyl 2-{[(6S*,7R*,8S*)-7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetate

IUCrData

Etify A. Bakhite¹  Elham A. Al-Taifi²  Shaaban K. Mohamed³  Joel T. Mague⁴  Mehmet Akkurt⁵ 

[1] Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt;Chemistry Department, Faculty of Science, Sana'a University, Sana'a, Yemen;Chemistry and Environmental Division, Manchester Metropolitan University, Manchester M1 5GD, England;Department of Chemistry, Tulane University, New Orleans, LA 70118, USA;Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey;

关键词: crystal structure;    isoquinoline;    tetrahydroisoquinolines;    hydrogen bonding;   

DOI  :  10.1107/S2414314617008689

来源: DOAJ

【 摘 要 】

In the title compound, C23H23ClN2O4S, the 4-chlorophenyl ring is inclined to the pyridine ring of the isoquinoline group by 71.86 (13)°. In the crystal, molecules are linked by pairs of O—H...O hydrogen bonds, forming inversion dimers, which stack along the b-axis direction. The methyl acetate group attached to the S atom is disordered over two sites in a 50:50 ratio, which appears to prevent close intermolecular contacts between the methyl groups.

【 授权许可】

Unknown