Space-Time Cluster Analysis of Invasive Meningococcal Disease

Emerging Infectious Diseases

关键词: Neisseria meningitidis;    invasive meningococcal disease;    outbreak;    cluster analysis;    space-time analysis;    secondary cases;   

DOI  :  10.3201/eid1009.030992

来源: DOAJ

【 摘 要 】

Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993–2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%–4.1%).

【 授权许可】

Unknown